Floxuridine

MedChem Express

Floxuridine [50-91-9]

10

50-91-9

Research Use Only

99.97

C9H11FN2O5

246.194

Floxuridine (5-Fluorouracil 2-deoxyriboside) is a pyrimidine analog and known as an oncology antimetabolite. Floxuridine inhibits Poly(ADP-Ribose) polymerase and induces DNA damage by activating the ATM and ATR checkpoint signaling pathways in vitro. Floxuridine is a extreamly potent inhibitor for S. aureus infection and induces cell apoptosis[1][2]. Floxuridine has antiviral effects against HSV and CMV[3].

OC[C@@H]1[C@@H](O)C[C@H](N2C(NC(C(F)=C2)=O)=O)O1

-20°C,2°C to 8°C

12352200