Bio-Connect

FLT3-IN-18 [752191-77-8]

HY-148522
MedChem Express
CAS Number752191-77-8
Product group Chemicals
Molecular Weight476.62
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Overview

  • Supplier
    MedChem Express
  • Product Name
    FLT3-IN-18 [752191-77-8]
  • Delivery Days Customer
    10
  • CAS Number
    752191-77-8
  • Certification
    Research Use Only
  • Molecular Formula
    C26H36N8O
  • Molecular Weight
    476.62
  • Scientific Description
    FLT3-IN-18 is a potent and selective FLT3 inhibitor with an IC50 value of 0.003 microM. FLT3-IN-18 induces apoptosis and cell cycle arrest at G1 phase. FLT3-IN-18 inhibits FLT3 and STAT5 phosphorylation. FLT3-IN-18 has the potential for the research of acute myeloid leukemia (AML)[1].
  • SMILES
    N[C@H](CC1)CC[C@@H]1NC2=NC(NC3=CC=C(N4CCOCC4)C=C3)=C5N=CN(C6CCCC6)C5=N2
  • UNSPSC
    12131703