FLT3/CDK4-IN-1 [2762296-44-4]

MedChem Express

FLT3/CDK4-IN-1 [2762296-44-4]

10

2762296-44-4

Research Use Only

C25H28F2N8

478.54

FLT3/CDK4-IN-1 is a potent, high selective and orally active FLT3/CDK4 dual inhibitor (IC50=11 and 7 nM for FLT3 and CDK4, respectively). FLT3/CDK4-IN-1 has antiproliferative activities against certain cancer cells. FLT3/CDK4-IN-1 has good antitumor effect in vivo[1].

CC(N1N=CC2=NC=C(C3=NC(NC4=CC=C(N5CCN(CC)CC5)C(F)=C4)=NC=C3F)C=C21)C

12352200