Flumazenil [78755-81-4]

TargetMol Chemicals

Flumazenil [78755-81-4]

4

78755-81-4

Chemical

Research Use Only

Flumazenil

99.62%

C15H14FN3O3

303.29

Flumazenil (Ro 15-1788) antagonizes the benzodiazepine binding site of the gamma-aminobutyric acid (GABA)/benzodiazepine receptor complex in the central nervous system (CNS), thereby preventing the chloride channel opening events and inhibiting neuronal hyperpolarization. As a result, flumazenil reverses benzodiazepine-induced effects including sedation, psychomotor deficits, amnesia, and hypoventilation in a dose-dependent manner. Flumazenil is an imidazobenzodiazepine derivative, effective in reversing benzodiazepine-induced activities.

3 years

CCOC(=O)c1ncn-2c1CN(C)C(=O)c1cc(F)ccc-21

-20°C

12352200