Flumethasone [2135-17-3]

MedChem Express

Flumethasone [2135-17-3]

5

2135-17-3

Research Use Only

99.84

C22H28F2O5

410.45

Flumethasone (Flumetasone) is an orally active, high selective and potent glucocorticoid receptor (GR) agonist. Flumethasone activates GR to inhibit nuclear factor kappa B (NF-kappaB)-mediated pro-inflammatory cytokine production (TNF-alpha, IL-1beta) and promotes anti-inflammatory gene expression (IL-10), while also regulating metabolic enzyme activity (tyrosine aminotransferase induction). Flumethasone is promising for research of inflammatory diseases, cancer, and endocrine regulation[1][2][3][4].

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-20°C,2°C to 8°C

12352200