Fluo-3FF (pentapotassium) [348079-14-1]

MedChem Express

Fluo-3FF (pentapotassium) [348079-14-1]

5

348079-14-1

Research Use Only

C35H21Cl2F2K5N2O13

981.94

Fluo-3FF pentapotassium is a cell-permeable acetoxy-methyl ester of Fluo-3FF, a fluorescent calcium indicator. Fluo-3FF is a di-fluorinated analog of Fluo-3 with a 100-fold lower affinity than Fluo-3 for calcium (Kds=42 and 0.4 microM, respectively). For its low affinity, Fluo-3FF is used for studying compartments with high concentrations of calcium, such as endoplasmic reticulum, where high affinity dyes will be insensitive to luminal fluctuations.

O=C1C=C2OC3=C(C(C4=CC(OCCOC5=C(C(F)=CC=C5N(CC(O[K])=O)CC(O[K])=O)F)=C(N(CC(O[K])=O)CC(O[K])=O)C=C4)=C2C=C1Cl)C=C(Cl)C(O[K])=C3

12162000