Fluorofenidone

MedChem Express

Fluorofenidone [848353-85-5]

10

848353-85-5

Research Use Only

99.78

C12H10FNO

203.21

Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway[1][2].

O=C1C=CC(C)=CN1C2=CC=CC(F)=C2

-20°C,2°C to 8°C

12352200