Fluorofenidone-d3

MedChem Express

Fluorofenidone-d3

10

Research Use Only

C12H7D3FNO

206.23

Fluorofenidone-d3 is deuterium labeled Fluorofenidone. Fluorofenidone (AKF-PD), an analogue of AMR69, shows equivalent antifibrotic activity, lower toxicity and longer half-life. Fluorofenidone (AKF-PD) attenuates the progression of renal interstitial fibrosis partly by suppressing NADPH oxidase and extracellular matrix (ECM) deposition via the PI3K/Akt signalling pathway[1][2].

O=C1C=CC(C)=CN1C2=C([2H])C=C([2H])C(F)=C2[2H]

12352200