FM19G11 [329932-55-0]

MedChem Express

FM19G11 [329932-55-0]

10

329932-55-0

Research Use Only

98.39

C23H17N3O8

463.40

FM19G11 is a hypoxia-inducible factor-1-alpha (HIF-1alpha) inhibitor, and it inhibits hypoxia-induced luciferase activity with an IC50 of 80 nM in HeLa cells. FM19G11 modulates other signaling pathways, including mTOR and PI3K/Akt/eNOS, when the HIF-1alpha pathway is inactivated under normoxic conditions[1][2].

O=C(OCC(C1=CC=C(C)C=C1)=O)C2=CC=CC(NC(C3=CC=C([N+]([O-])=O)C=C3[N+]([O-])=O)=O)=C2

2°C to 8°C

12352200