Fmoc-L-Asn(EDA-N3)-OH [2616562-74-2]

TargetMol Chemicals

Fmoc-L-Asn(EDA-N3)-OH [2616562-74-2]

9

Research Use Only

C21H21N5O5

423.42

Fmoc-L-Asn(EDA-N3)-OH is a chemical compound equipped with an azide group used in click chemistry. Reports in the literature have demonstrated its application in the modification of alpha-amanitin, the deadliest member of the amatoxin peptide family produced by the death cap mushroom. alpha-Amanitin is a highly lethal natural compound (LD50=50-100 microg/kg), an orally ingested rigid bicyclic octapeptide, acting as a highly selective conformational inhibitor of RNA polymerase II.

C(OC(N[C@@H](CC(NCCN=[N+]=[N-])=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

-20°C

12352200