Fmoc-L-Lys(4-N3-Z)-OH

MedChem Express

Fmoc-L-Lys(4-N3-Z)-OH [1446511-14-3]

10

Research Use Only

C29H29N5O6

543.57

Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent containing an azide group. Fmoc-L-Lys(4-N3-Z)-OH acts as Lysine building-block for SPPS containing an Azide moiety as a bioorthogonal ligation handle, an infrared probe and a photo-affinity reagent. It can be decaged by trans-cyclooctenols via a strain-promoted 1,3-dipolar cycloaddition[1][2]. Fmoc-L-Lys(4-N3-Z)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(O)[C@H](CCCCNC(OCC1=CC=C(N=[N+]=[N-])C=C1)=O)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

41115800