Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester

MedChem Express

Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester

10

Research Use Only

C38H42F5N5O9

807.76

Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Fmoc-NH-Azide-PEG4-L-Lysine-PFP ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

O=C(OC1=C(F)C(F)=C(F)C(F)=C1F)C(NC(OCC2C(C=CC=C3)=C3C4=C2C=CC=C4)=O)CCCCNC(CCOCCOCCOCCOCCN=[N+]=[N-])=O

41115800