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ProductsBack/FMS586 (free base) [302556-51-0]

FMS586 (free base) [302556-51-0]

HY-118768
MedChem Express
CAS Number302556-51-0
Product group Chemicals
Molecular Weight390.52
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Overview

  • Supplier
    MedChem Express
  • Product Name
    FMS586 (free base) [302556-51-0]
  • Delivery Days Customer
    9
  • CAS Number
    302556-51-0
  • Certification
    Research Use Only
  • Molecular Formula
    C24H30N4O
  • Molecular Weight
    390.52
  • Scientific Description
    FMS586 free base is a selective neuropeptide Y Y5 receptor antagonist with oral activity. FMS586 can completely block the significant increase in adrenocorticotropic hormone (ACTH) and cortisol caused by the Y(5) selective agonist hPP. FMS586 also reversed the significant upregulation of adrenocorticotropic hormone (CRF) and antidiuretic hormone (AVP) mRNA expression induced by central injection of hPP. FMS586 provides the first evidence that selective stimulation of Y(5) receptors triggers activation of the HPA axis[1].
  • SMILES
    O=C(N(CCC1=CC=NC=C1)C)NC2=CC3=C(N(C4=C3CCCC4)C(C)C)C=C2
  • UNSPSC
    12352200

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