Fnk antibody

GeneTex

Fnk antibody

9

WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

PLK3

polo like kinase 3

CNK, FNK, PLK-3, PRK, serine/threonine-protein kinase PLK3, FGF-inducible kinase, cytokine-inducible serine/threonine-protein kinase, proliferation-related kinase

Rabbit

IgG

Serine/threonine-protein kinase PLK3

The protein encoded by this gene is a member of the highly conserved polo-like kinase family of serine/threonine kinases. Members of this family are characterized by an amino-terminal kinase domain and a carboxy-terminal bipartite polo box domain that functions as a substrate-binding motif and a cellular localization signal. Polo-like kinases are important regulators of cell cycle progression. This gene has also been implicated in stress responses and double-strand break repair. In human cell lines, this protein is reported to associate with centrosomes in a microtubule-dependent manner, and during mitosis, the protein becomes localized to the mitotic apparatus. Expression of a kinase-defective mutant results in abnormal cell morphology caused by changes in microtubule dynamics and mitotic arrest followed by apoptosis. [provided by RefSeq, Sep 2015]

-20°C or -80°C,2°C to 8°C

12352203