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ProductsBack/FOG2 antibody

FOG2 antibody

Research Use Only
GTX110166
GeneTex
ApplicationsWestern Blot
DownloadDatasheet
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetZFPM2
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Overview

  • Supplier
    GeneTex
  • Product Name
    FOG2 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.96 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID23414
  • Target name
    ZFPM2
  • Target description
    zinc finger protein, FOG family member 2
  • Target synonyms
    DIH3; FOG2; FOG-2; friend of GATA 2; friend of GATA protein 2; Friend of GATA2; hFOG-2; SRXY9; transcription factor GATA4, modulator of; ZC2HC11B; zinc finger protein 89B; zinc finger protein ZFPM2; zinc finger protein, multitype 2; ZNF89B
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8WW38
  • Protein Name
    Zinc finger protein ZFPM2
  • Scientific Description
    The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • CRISPR/CAS9 ablation of individual miRNAs from a miRNA family reveals their individual efficacies for regulating cardiac differentiation. Zhang Z et al., 2018 Apr, Mech Dev
    Read more
  • MicroRNA-200c Promotes Suppressive Potential of Myeloid-Derived Suppressor Cells by Modulating PTEN and FOG2 Expression. Mei S et al., 2015, PLoS One
    Read more
  • Mutation within the hinge region of the transcription factor Nr2f2 attenuates salt-sensitive hypertension. Kumarasamy S et al., 2015 Feb 17, Nat Commun
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  • The miR-17-92 cluster regulates FOG-2 expression and inhibits proliferation of mouse embryonic cardiomyocytes. Xiang R et al., 2012 Feb, Braz J Med Biol Res
    Read more