FOLR1, Canine (HEK293, Fc)
HY-P76936
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameFOLR1, Canine (HEK293, Fc)
- Delivery Days Customer10
- CertificationResearch Use Only
- Gene ID609612
- Target nameLOC609612
- Target descriptionfolate receptor alpha
- Target synonymsFOLR1, folate receptor alpha, folate receptor 1 (adult)
- Scientific DescriptionFOLR1 is a folic acid receptor that binds to folic acid and reductive folic acid derivatives and promotes the entry of 5-methyltetrahydrofolate and folate analogs into the cell interior. FOLR1 enhances the stability and nuclear translocation of beta-catenin through the EGFR/AKT/GSK3beta axis, thereby promoting the proliferation and migration of laryngeal squamous cell carcinoma (LSCC). FOLR1 is highly expressed in a variety of tumors and is a potential prognostic and therapeutic target for many cancers. FOLR1 Protein, Canine (HEK293, Fc) is the recombinant canine-derived FOLR1 protein, expressed by HEK293 , with C-hFc labeled tag.
- UNSPSC41116100
- SpeciesCanine