Bio-Connect

FOLR1, Canine (HEK293, His)

HY-P76937
MedChem Express
Product group Proteins / Signaling Molecules
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    MedChem Express
  • Product Name
    FOLR1, Canine (HEK293, His)
  • Delivery Days Customer
    5
  • Certification
    Research Use Only
  • Estimated Purity
    96.00
  • Gene ID609612
  • Target name
    LOC609612
  • Target description
    folate receptor alpha
  • Target synonyms
    FOLR1, folate receptor alpha, folate receptor 1 (adult)
  • Scientific Description
    FOLR1 is a folic acid receptor that binds to folic acid and reductive folic acid derivatives and promotes the entry of 5-methyltetrahydrofolate and folate analogs into the cell interior. FOLR1 enhances the stability and nuclear translocation of beta-catenin through the EGFR/AKT/GSK3beta axis, thereby promoting the proliferation and migration of laryngeal squamous cell carcinoma (LSCC). FOLR1 is highly expressed in a variety of tumors and is a potential prognostic and therapeutic target for many cancers. FOLR1 Protein, Canine (HEK293, His) is the recombinant canine-derived FOLR1 protein, expressed by HEK293 , with C-His labeled tag.
  • Storage Instruction
    -20°C
  • UNSPSC
    41116100
  • Species
    Canine