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FOLR1, Cynomolgus/Rhesus Macaque (209a.a, HEK293, His)

Name: FOLR1, Cynomolgus/Rhesus Macaque (209a.a, HEK293, His)
SKU: HY-P77664_M09
Availability: BackOrder

HY-P77664

Product group Proteins / Signaling Molecules

Overview

Supplier
MedChem Express
Product Name
FOLR1, Cynomolgus/Rhesus Macaque (209a.a, HEK293, His)
Delivery Days Customer
10
Certification
Research Use Only
Gene ID718388
Target name
FOLR1
Target description
folate receptor alpha
Target synonyms
EGK_06645, folate receptor alpha, folate receptor 1
Scientific Description
FOLR1 is a folic acid receptor that binds to folic acid and reductive folic acid derivatives and promotes the entry of 5-methyltetrahydrofolate and folate analogs into the cell interior. FOLR1 enhances the stability and nuclear translocation of beta-catenin through the EGFR/AKT/GSK3beta axis, thereby promoting the proliferation and migration of laryngeal squamous cell carcinoma (LSCC). FOLR1 is highly expressed in a variety of tumors and is a potential prognostic and therapeutic target for many cancers. FOLR1 Protein, Cynomolgus/Rhesus Macaque (209a.a, HEK293, His) is the recombinant cynomolgus, Rhesus Macaque-derived FOLR1 protein, expressed by HEK293 , with C-His labeled tag.
UNSPSC
41116100
Species
Primate