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Forodesine hydrochloride [284490-13-7]

Forodesine hydrochloride [284490-13-7]

T11313
TargetMol Chemicals
CAS Number284490-13-7
Product group Chemicals
Molecular Weight302.71
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Forodesine hydrochloride
  • Delivery Days Customer
    19
  • CAS Number
    284490-13-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Forodesine hydrochloride
  • Molecular Formula
    C11H15ClN4O4
  • Molecular Weight
    302.71
  • Scientific Description
    Forodesine hydrochloride (BCX-1777 hydrochloride), a potent inhibitor of human lymphocyte proliferation, effectively induces apoptosis in leukemic cells by elevating dGTP levels. This compound is an orally active, highly potent purine nucleoside phosphorylase (PNP) inhibitor, demonstrating IC50 values between 0.48 to 1.57 nM across human, mouse, rat, monkey, and dog PNP.
  • Shelf life instruction
    3 years
  • SMILES
    Cl.OC[C@H]1N[C@H]([C@H](O)[C@@H]1O)c1c[nH]c2c1[nH]cnc2=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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