Foropafant

MedChem Express

Foropafant [136468-36-5]

10

136468-36-5

Research Use Only

99.97

C28H40N4S

464.72

Foropafant (SR27417) highly potent, competitive, selective and orally active antagonist of platelet-activating factor ( PAF ) receptor, with a K i value of 57 pM for [ 3 H]PAF binding, at least 5-fold lower than that of unlabeled PAF itself. Foropafant potently inhibits PAF-induced aggregation of rabbit and human platelets [1] .

CC(C)C1=CC(C(C)C)=C(C2=CSC(=N2)N(CCN(C)C)CC2=CC=CN=C2)C(=C1)C(C)C

-20°C,2°C to 8°C

12352200