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Forskolin

Research Use Only
HY-15371
MedChem Express
CAS Number66575-29-9
Product group Chemicals
Estimated Purity99.78
Molecular Weight410.50
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Packing Size
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Forskolin [66575-29-9]
  • Delivery Days Customer
    5
  • CAS Number
    66575-29-9
  • Certification
    Research Use Only
  • Estimated Purity
    99.78
  • Molecular Formula
    C22H34O7
  • Molecular Weight
    410.50
  • Scientific Description
    Forskolin (Coleonol) is a potent adenylate cyclase activator with an IC50 of 41 nM and an EC50 of 0.5 microM for type I adenylyl cyclase[1]. Forskolin is also an inducer of intracellular cAMP formation[2]. Forskolin induces differentiation of various cell types and activates pregnane X receptor (PXR) and FXR[3]. Forskolin exerts a inotropic effect on the heart, and has platelet antiaggregatory and antihypertensive actions. Forskolin also induces autophagy[4][5].
  • SMILES
    O=C1[C@@]2(O)[C@]([C@@H](OC(C)=O)[C@@H](O)[C@@]3([H])C(C)(C)CC[C@H](O)[C@@]32C)(C)O[C@@](C)(C=C)C1
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200