Fosmanogepix [2091769-17-2]

TargetMol Chemicals

Fosmanogepix [2091769-17-2]

14

2091769-17-2

Chemical

Research Use Only

Fosmanogepix

C22H21N4O6P

468.4

Fosmanogepix (APX001) is a first-in-class, orally available broad-spectrum antifungal agent. It acts as an N-phosphonooxymethyl prodrug that undergoes rapid and complete metabolism by systemic alkaline phosphatases. This metabolism leads to the formation of the active moiety, APX001A. Fosmanogepix (APX001), with its ability to target the highly conserved Gwt1 fungal enzyme, holds great potential for the development of treatments against invasive fungal infections.

3 years

O=P([O-])(O)OC[N+]1=CC=CC(C=2ON=C(C2)CC3=CC=C(C=C3)COC4=NC=CC=C4)=C1N

-20°C

12352200