Fostamatinib

MedChem Express

Fostamatinib [901119-35-5]

10

901119-35-5

Research Use Only

99.50

C23H26FN6O9P

580.46

Fostamatinib (R788) is the oral proagent of the active compound R406 [1] . R406 is an orally available and competitive Syk/FLT3 inhibitor with a K i of 30 nM and an IC 50 of 41 nM [2] . R406 also inhibits Lyn (IC 50 =63 nM) and Lck (IC 50 =37 nM) [3] .

COC1=CC(NC2=NC=C(C(NC3=NC(N4COP(O)(O)=O)=C(C=C3)OC(C)(C)C4=O)=N2)F)=CC(OC)=C1OC

-20°C,2°C to 8°C

12352200