FOXO3A antibody [C3], C-term
GTX100277
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mammals, Mouse, Rat, Xenopus
TargetFOXO3
Overview
- SupplierGeneTex
- Product NameFOXO3A antibody [C3], C-term
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.56 mg/ml
- ConjugateUnconjugated
- Gene ID2309
- Target nameFOXO3
- Target descriptionforkhead box O3
- Target synonymsAF6q21; FKHRL1; FKHRL1P2; forkhead box O3A; forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; forkhead in rhabdomyosarcoma-like 1; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; FOXO2; FOXO3A; FOXO3A-
- HostRabbit
- IsotypeIgG
- Protein IDO43524
- Protein NameForkhead box protein O3
- Scientific DescriptionThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]
- ReactivityHuman, Mammals, Mouse, Rat, Xenopus
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease.Read more
- The Expression of FOXO3a as a Forensic Diagnostic Tool in Cases of Traumatic Brain Injury: An Immunohistochemical Study.Read more
- Cisplatin or Doxorubicin Reduces Cell Viability via the PTPIVA3-JAK2-STAT3 Cascade in Hepatocellular Carcinoma.Read more
- FOXO3 Depletion as a Marker of Compression-Induced Apoptosis in the Ligature Mark: An Immunohistochemical Study.Read more
- Effective-component compatibility of Bufei Yishen formula protects COPD rats against PM2.5-induced oxidative stress via miR-155/FOXO3a pathway. Li J et al., 2021 Nov 10, Ecotoxicol Environ SafRead more
- FGF19 protects skeletal muscle against obesity-induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT-1/PGC-alpha pathway. Guo A et al., 2021 Apr, J Cell Mol MedRead more
- The regulation of Akt and FoxO transcription factors during dehydration in the African clawed frog (Xenopus laevis). Luu BE et al., 2020 Nov, Cell Stress ChaperonesRead more
- Abeta exacerbates alpha-synuclein-induced neurotoxicity through impaired insulin signaling in alpha-synuclein-overexpressed human SK-N-MC neuronal cells. Chang CC et al., 2018 Jan, CNS Neurosci TherRead more
- Transcriptional activation of muscle atrophy promotes cardiac muscle remodeling during mammalian hibernation. Zhang Y et al., 2016, PeerJRead more
- Sp1-mediated microRNA-182 expression regulates lung cancer progression. Yang WB et al., 2014 Feb 15, OncotargetRead more