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FOXO3A antibody [C3], C-term

GTX100277
GeneTex
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetFOXO3
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Overview

  • Supplier
    GeneTex
  • Product Name
    FOXO3A antibody [C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.56 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2309
  • Target name
    FOXO3
  • Target description
    forkhead box O3
  • Target synonyms
    AF6q21, FKHRL1, FKHRL1P2, FOXO2, FOXO3A, forkhead box protein O3, FOXO3A-, forkhead box O3A, forkhead homolog (rhabdomyosarcoma) like 1, forkhead in rhabdomyosarcoma-like 1, forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDO43524
  • Protein Name
    Forkhead box protein O3
  • Scientific Description
    This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Fletcher E, Miserlis D, Sorokolet K, et al. Diet-induced obesity augments ischemic myopathy and functional decline in a murine model of peripheral artery disease. Transl Res. 2023,260:17-31. doi: 10.1016/j.trsl.2023.05.002
    Read this paper
  • Maiese A, Spina F, Visi G, et al. The Expression of FOXO3a as a Forensic Diagnostic Tool in Cases of Traumatic Brain Injury: An Immunohistochemical Study. Int J Mol Sci. 2023,24(3). doi: 10.3390/ijms24032584
    Read this paper
  • Li CJ, Tsai HW, Chen YL, et al. Cisplatin or Doxorubicin Reduces Cell Viability via the PTPIVA3-JAK2-STAT3 Cascade in Hepatocellular Carcinoma. J Hepatocell Carcinoma. 2023,10:123-138. doi: 10.2147/JHC.S385238
    Read this paper
  • Maiese A, Manetti AC, Santoro P, et al. FOXO3 Depletion as a Marker of Compression-Induced Apoptosis in the Ligature Mark: An Immunohistochemical Study. Int J Mol Sci. 2023,24(2). doi: 10.3390/ijms24021396
    Read this paper
  • Li J, Wang J, Li Y, et al. Effective-component compatibility of Bufei Yishen formula protects COPD rats against PM2.5-induced oxidative stress via miR-155/FOXO3a pathway. Ecotoxicol Environ Saf. 2021,228:112918. doi: 10.1016/j.ecoenv.2021.112918
    Read this paper
  • Guo A, Li K, Tian HC, et al. FGF19 protects skeletal muscle against obesity-induced muscle atrophy, metabolic derangement and abnormal irisin levels via the AMPK/SIRT-1/PGC-α pathway. J Cell Mol Med. 2021,25(7):3585-3600. doi: 10.1111/jcmm.16448
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  • Luu BE, Zhang Y, Storey KB. The regulation of Akt and FoxO transcription factors during dehydration in the African clawed frog (Xenopus laevis). Cell Stress Chaperones. 2020,25(6):887-897. doi: 10.1007/s12192-020-01123-y
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  • Chang CC, Li HH, Chang YT, et al. Aβ exacerbates α-synuclein-induced neurotoxicity through impaired insulin signaling in α-synuclein-overexpressed human SK-N-MC neuronal cells. CNS Neurosci Ther. 2018,24(1):47-57. doi: 10.1111/cns.12772
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  • Zhang Y, Aguilar OA, Storey KB. Transcriptional activation of muscle atrophy promotes cardiac muscle remodeling during mammalian hibernation. PeerJ. 2016,4:e2317. doi: 10.7717/peerj.2317
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  • Yang WB, Chen PH, Hsu T 1st, et al. Sp1-mediated microRNA-182 expression regulates lung cancer progression. Oncotarget. 2014,5(3):740-53.
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