WB analysis of various sample lysates using GTX54036 Frataxin antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of various sample lysates using GTX54036 Frataxin antibody. Dilution : 1:1000 Loading : 25microg per lane
Frataxin antibody
GTX54036
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetFXN
Overview
- SupplierGeneTex
- Product NameFrataxin antibody
- Delivery Days Customer7
- Application Supplier NoteWB: 1:500 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:50 - 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2395
- Target nameFXN
- Target descriptionfrataxin
- Target synonymsCyaY; FA; FARR; frataxin, mitochondrial; FRDA; Friedreich ataxia protein; X25
- HostRabbit
- IsotypeIgG
- Protein IDQ16595
- Protein NameFrataxin, mitochondrial
- Scientific DescriptionThis nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Reverse Phase Protein Array Reveals Correlation of Retinoic Acid Metabolism With Cardiomyopathy in Friedreichs Ataxia. Napierala JS et al., 2021, Mol Cell ProteomicsRead more
- Mitochondrial damage and senescence phenotype of cells derived from a novel frataxin G127V point mutation mouse model of Friedreichs ataxia. Fil D et al., 2020 Jul 27, Dis Model MechRead more
- Defining Transcription Regulatory Elements in the Human Frataxin Gene: Implications for Gene Therapy. Li J et al., 2020 Aug, Hum Gene TherRead more
- Long-term voluntary running prevents the onset of symptomatic Friedreichs ataxia in mice. Zhao H et al., 2020 Apr 8, Sci RepRead more
- Hypoxia Rescues Frataxin Loss by Restoring Iron Sulfur Cluster Biogenesis. Ast T et al., 2019 May 30, CellRead more
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