Frizzled-4/CD344, Human (HEK293, His)

MedChem Express

Frizzled-4/CD344, Human (HEK293, His)

10

Research Use Only

98.00

FZD4

frizzled class receptor 4

CD344, EVR1, FEVR, FZD4S, Fz-4, Fz4, FzE4, GPCR, hFz4, frizzled-4, WNT receptor frizzled-4, frizzled 4, seven transmembrane spanning receptor, frizzled family receptor 4, frizzled homolog 4

Frizzled-4

The Frizzled-4/CD344 protein is a receptor for Wnt proteins and is associated with the classical beta-catenin pathway, activating disheveled proteins, inhibiting GSK-3 kinase, and triggering Wnt target genes. In retinal vascularization, it acts as a receptor for Wnt proteins and Norrin (NDP), stimulating beta-catenin accumulation and LEF/TCF-mediated transcription. Frizzled-4/CD344 Protein, Human (HEK293, His) is the recombinant human-derived Frizzled-4/CD344 protein, expressed by HEK293 , with C-His labeled tag.

-20°C

41116100