Frizzled 7 antibody, C-term

GeneTex

Frizzled 7 antibody, C-term

9

WB: 0.3-1microg/ml. IHC-P: 5microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

FZD7

frizzled class receptor 7

frizzled 7, seven transmembrane spanning receptor; frizzled family receptor 7; frizzled homolog 7; Frizzled, drosophila, homolog of, 7; frizzled-7; fz-7; FzE3; hFz7

Goat

IgG

Frizzled-7

Members of the frizzled gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD7 protein contains an N-terminal signal sequence, 10 cysteine residues typical of the cysteine-rich extracellular domain of Fz family members, 7 putative transmembrane domains, and an intracellular C-terminal tail with a PDZ domain-binding motif. FZD7 gene expression may downregulate APC function and enhance beta-catenin-mediated signals in poorly differentiated human esophageal carcinomas. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203