FSH receptor antagonist 1

MedChem Express

FSH receptor antagonist 1 [487064-35-7]

5

Research Use Only

C33H32N2O2

488.62

FSH receptor antagonist 1 (compound 10) is a potent antagonist of the G(s)-protein-coupled human follicle-stimulating hormone (FSH) receptor. FSH receptor antagonist 1 exhibits an IC50 of 28 nM on a cell line expressing the human FSH receptor. FSH receptor antagonist 1 significantly inhibits follicle growth and ovulation in an ex vivo mouse model[1].

O=C(C1=CC=C(C2=CC=CC=C2)C=C1)NC3=CC=C4C(C(C)(CC(C)(C)N4C(C)=O)C5=CC=CC=C5)=C3

12131703