FT113

MedChem Express

FT113 [1630808-89-7]

5

1630808-89-7

Research Use Only

99.39

C22H20FN3O4

409.41

FT113 is a potent and orally active fatty acid synthase (FASN) inhibitor, with an IC 50 of 213 nM for full-length recombinant human FASN enzyme. In cell-based assay, FT113 blocks FASN activity in BT474 cells (IC 50 , 90 nM). FT113 shows anti-proliferative activity, and exhibits anti-cancer activity both in vitro and in vivo [1] .

O=C(C1(CC1)O)N2CCN(C(C3=CC=C(C4=NC5=C(C=C(F)C=C5)O4)C=C3)=O)CC2

-20°C,2°C to 8°C

12352200