FTI-2148 diTFA

Biorbyt

FTI-2148 diTFA

10

817586-01-9

Research Use Only

98.00%

C26H29F3N4O5S

566.6

FTI-2148 diTFA, a dual inhibitor targeting both farnesyl transferase (FT-1) and geranylgeranyl transferase-1 (GGT-1), functions as a RAS C-terminal mimetic. It exhibits potent inhibitory capabilities with IC50 values of 1.4 nM for FT-1 and 1.7 microM for GGT-1, respectively.

OC(=O)C(F)(F)F.CSCC[C@H](NC(=O)c1ccc(CNCc2cnc[nH]2)cc1-c1ccccc1C)C(O)=O

-20°C

12352200