FTO (mouse) (rec.) (His)

AdipoGen Life Sciences

FTO (mouse) (rec.) (His)

10

Research Use Only

0.5 mg/ml

>90%

Alpha-ketoglutarate-dependent dioxygenase FTO

FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse fused toes mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol. - Protein. Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag. Source: E. coli. Endotoxin content: <1EU/microg purified protein (LAL test; Lonza). Liquid. 0.2microm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl. Purity: >90% (SDS-PAGE). FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse fused toes mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.

-20°C,2°C to 8°C

12352202