Fulvestrant

MedChem Express

Fulvestrant [129453-61-8]

10

129453-61-8

Research Use Only

99.95

C32H47F5O3S

606.77

Fulvestrant (ICI 182780) is a pure antiestrogen and a potent estrogen receptor (ER) antagonist with an IC 50 of 9.4 nM. Fulvestrant is also a GPR30 agonist. Fulvestrant effectively inhibits the growth of ER -positive MCF-7 cells with an IC 50 of 0.29 nM. Fulvestrant also induces autophagy and has antitumor efficacy [1] .

C[C@@]12[C@@H](O)CC[C@@]1([H])[C@]3([H])[C@H](CCCCCCCCCS(CCCC(F)(F)C(F)(F)F)=O)CC4=C(C=CC(O)=C4)[C@@]3([H])CC2

-20°C,2°C to 8°C

12352200