Furosemide

MedChem Express

Furosemide [54-31-9]

10

54-31-9

Research Use Only

99.90

C12H11ClN2O5S

330.74

Furosemide is a potent and orally active inhibitor of Na + /K + /2Cl - ?(NKCC) cotransporter , NKCC1 and NKCC2 [1] .?Furosemide is also a GABA A ?receptors antagonist and displays 100-fold selectivity for?alpha6-containing receptors than?alpha1-containing receptors. Furosemide acts as a loop diuretic and used for the study of congestive heart failure, hypertension and edema [2] .

O=C(O)C1=CC(S(=O)(N)=O)=C(Cl)C=C1NCC2=CC=CO2

2°C to 8°C

12352200