FX-909

Biorbyt

FX-909

10

Research Use Only

C17H10F2N2O3S

360.3347096

FX-909 (FX 909) is a first-in-class inverse agonist of the peroxisome proliferator-activated receptor gamma (PPARG) lineage transcription factor with EC50 of 1 nM and shows > 2000-fold selectivity for PPARG over PPARA/PPARD - acting through a mechanism that promotes a repressive conformation of PPARG.

C1(F)C=C2C(=C(F)C=1)C(=O)C=C(C1=C(C=CC(C#N)=C1)S(=O)(=O)C)N2

12352200