ProductsBack/FYN antibody [N1N3]

FYN antibody [N1N3]

Name: FYN antibody [N1N3]
SKU: GTX101189_G10
Availability: BackOrder

GTX101189

ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry

Product group Antibodies

TargetFYN

Overview

Supplier
GeneTex
Product Name
FYN antibody [N1N3]
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID2534
Target name
FYN
Target description
FYN proto-oncogene, Src family tyrosine kinase
Target synonyms
SLK, SYN, p59-FYN, tyrosine-protein kinase Fyn, FYN oncogene related to SRC, FGR, YES, OKT3-induced calcium influx regulator, c-syn protooncogene, proto-oncogene Syn, proto-oncogene c-Fyn, src-like kinase, src/yes-related novel, tyrosine kinase p59fyn(T)
Host
Rabbit
Isotype
IgG
Protein IDP06241
Protein Name
Tyrosine-protein kinase Fyn
Scientific Description
This gene is a member of the protein-tyrosine kinase oncogene family. It encodes a membrane-associated tyrosine kinase that has been implicated in the control of cell growth. The protein associates with the p85 subunit of phosphatidylinositol 3-kinase and interacts with the fyn-binding protein. Alternatively spliced transcript variants encoding distinct isoforms exist. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Terasaki M, Takahashi S, Nishimura R, et al. A Marine Carotenoid of Fucoxanthinol Accelerates the Growth of Human Pancreatic Cancer PANC-1 Cells. Nutr Cancer. 2022,74(1):357-371. doi: 10.1080/01635581.2020.1863994
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Huang C, Huang YL, Wang CC, et al. Ampelopsins A and C Induce Apoptosis and Metastasis through Downregulating AxL, TYRO3, and FYN Expressions in MDA-MB-231 Breast Cancer Cells. J Agric Food Chem. 2019,67(10):2818-2830. doi: 10.1021/acs.jafc.8b06444
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Gingras J, Gawor M, Bernadzki KM, et al. Α-Dystrobrevin-1 recruits Grb2 and α-catulin to organize neurotransmitter receptors at the neuromuscular junction. J Cell Sci. 2016,129(5):898-911. doi: 10.1242/jcs.181180
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Chang SF, Chen LJ, Lee PL, et al. Different modes of endothelial-smooth muscle cell interaction elicit differential β-catenin phosphorylations and endothelial functions. Proc Natl Acad Sci U S A. 2014,111(5):1855-60. doi: 10.1073/pnas.1323761111
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