The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA032335(FZD6 Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200)

FZD6 Antibody

Name: FZD6 Antibody
SKU: CSB-PA032335_C90
Availability: BackOrder

CSB-PA032335

ApplicationsELISA, ImmunoHistoChemistry

Product group Antibodies

TargetFZD6

Overview

Supplier
Cusabio
Product Name
FZD6 Antibody
Delivery Days Customer
20
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID8323
Target name
FZD6
Target description
frizzled class receptor 6
Target synonyms
frizzled 6, seven transmembrane spanning receptor; frizzled family receptor 6; frizzled homolog 6; frizzled-6; FZ6; FZ-6; HFZ6; NDNC1; NDNC10; seven transmembrane helix receptor
Host
Rabbit
Isotype
IgG
Protein IDO60353
Protein Name
Frizzled-6
Scientific Description
This gene represents a member of the frizzled gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.
Storage Instruction
-20°C or -80°C
UNSPSC
12352203

FZD6 Antibody

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Overview

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