G-1749 [2245057-57-0]

TargetMol Chemicals

G-1749 [2245057-57-0]

16

Research Use Only

99.86%

C28H30N6O3

498.59

G-1749 does not alter the monomer-dimer equilibrium of IRE, stimulates the RNase activity of unphosphorylated IRE1 and inhibits IRE1-3P, and significantly increases the RNase activity of IRE1-KR-0P.

CCOC(=O)Nc1cccc2c(Oc3ncccc3-c3ccnc(N[C@H]4CCCNC4)n3)c(C)ccc12

-20°C

12352200