GNAI3 antibody
GTX14246
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetGNAI3
Overview
- SupplierGeneTex
- Product NameG protein alpha Inhibitor 3 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500. ICC/IF: 1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID2773
- Target nameGNAI3
- Target descriptionG protein subunit alpha i3
- Target synonyms87U6; ARCND1; g(i) alpha-3; guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3; guanine nucleotide-binding protein G(i) subunit alpha; guanine nucleotide-binding protein G(i) subunit alpha-3; guanine nucleotide-binding protein G(k) subunit alpha
- HostChicken
- IsotypeIgY
- Protein IDP08754
- Protein NameGuanine nucleotide-binding protein G(k) subunit alpha
- Scientific DescriptionGAI3 is the a subunit of inhibitory trimeric G protein (Gi), which inhibits adenylate cyclase once its G protein coupled receptors (GPCR) such as a2 adrenergic receptors are activated. GAI3 can be inactivated by pertussis toxin. Guanine nucleotide binding proteins are involved as modulators or transducers in various transmembrane signaling systems. G(k) is the stimulatory G protein of receptor regulated K(+) channels.
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling. Landin Malt A et al., 2020 Oct 5, J Cell BiolRead more