G140 [2369751-07-3]

MedChem Express

G140 [2369751-07-3]

10

2369751-07-3

Research Use Only

99.17

C17H16Cl2N4O2

379.24

G140 is a potent and selective inhibitor of cyclic GMP-AMP synthase (cGAS), with IC50s of 14.0 nM and 442 nM for h-cGAS and m-cGAS, respectively. G140 has anti-inflammatory activity[1].

OCC(N(C1)CCC(N2)=C1C3=C2C(Cl)=C(Cl)C=C3C4=NN(C)C=C4)=O

-20°C, 3 years; 4°C, 2 years (Powder)

12352200