G36 [1392487-51-2]

MedChem Express

G36 [1392487-51-2]

10

1392487-51-2

Research Use Only

99.66

C22H22BrNO2

412.32

G-36 is a cell-permeable nonsteroidal antagonist of the G protein-coupled estrogen receptor (GPER/GPR30), which selectively inhibits estrogen-mediated PI3K activation through GPER, rather than Eralpha. G-36 also inhibits estrogen-mediated calcium mobilization (IC50=112 nM). G-36 is promising for research in the field of cancer[1][2].

CC(C1=CC2=C(N[C@@H](C3=C(Br)C=C(OCO4)C4=C3)[C@]5([H])[C@@]2([H])C=CC5)C=C1)C

-20°C

12352200