Bio-Connect

G5-7

M31205
AbMole BioScience
CAS Number939681-36-4
Product group Chemicals
Molecular Weight383.39
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Overview

  • Supplier
    AbMole BioScience
  • Product Name
    G5-7
  • Delivery Days Customer
    9
  • CAS Number
    939681-36-4
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Molecular Formula
    C22H19F2NO3
  • Molecular Weight
    383.39
  • Scientific Description
    G5-7 is an orally active and allosteric JAK2 inhibitor, selectively inhibits JAK2 mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 induces cell cycle arrest, apoptosis and possesses antiangiogenic effect. G5-7 has the potential for glioma study.
  • SMILES
    CCOC(=O)N1CC(=C/C2=CC=CC=C2F)/C(=O)C(/C1)=C\C3=CC=CC=C3F
  • Storage Instruction
    Powder -20°C
  • UNSPSC
    12352200