G5-7

AbMole BioScience

G5-7

9

939681-36-4

Chemical

Research Use Only

C22H19F2NO3

383.39

G5-7 is an orally active and allosteric JAK2 inhibitor, selectively inhibits JAK2 mediated phosphorylation and activation of EGFR (Tyr1068) and STAT3 by binding to JAK2. G5-7 induces cell cycle arrest, apoptosis and possesses antiangiogenic effect. G5-7 has the potential for glioma study.

CCOC(=O)N1CC(=C/C2=CC=CC=C2F)/C(=O)C(/C1)=C\C3=CC=CC=C3F

Powder -20°C

12352200