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G6PD antibody

GTX101212
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetG6PD
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Overview

  • Supplier
    GeneTex
  • Product Name
    G6PD antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    6.37 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2539
  • Target name
    G6PD
  • Target description
    glucose-6-phosphate dehydrogenase
  • Target synonyms
    epididymis secretory sperm binding protein; G6PD1; glucose-6-phosphate 1-dehydrogenase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP11413
  • Protein Name
    Glucose-6-phosphate 1-dehydrogenase
  • Scientific Description
    This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer. Anderton B et al., 2017 Apr, EMBO Rep
    Read more
  • Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. May EW et al., 2014 Dec, Pharmacol Res
    Read more
  • Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells. Li B et al., 2014 Apr, Aging Cell
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