ProductsBack/G6PD antibody

G6PD antibody

Name: G6PD antibody
SKU: GTX101212_G10
Availability: BackOrder

GTX101212

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

TargetG6PD

Overview

Supplier
GeneTex
Product Name
G6PD antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
6.37 mg/ml
Conjugate
Unconjugated
Gene ID2539
Target name
G6PD
Target description
glucose-6-phosphate dehydrogenase
Target synonyms
CNSHA1, G6PD1, glucose-6-phosphate 1-dehydrogenase, epididymis secretory sperm binding protein
Host
Rabbit
Isotype
IgG
Protein IDP11413
Protein Name
Glucose-6-phosphate 1-dehydrogenase
Scientific Description
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

Anderton B, Camarda R, Balakrishnan S, et al. MYC-driven inhibition of the glutamate-cysteine ligase promotes glutathione depletion in liver cancer. EMBO Rep. 2017,18(4):569-585. doi: 10.15252/embr.201643068
Read this paper
May EW, Lin ST, Lin CC, et al. Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. Pharmacol Res. 2014,90:1-17. doi: 10.1016/j.phrs.2014.08.007
Read this paper
Li B, Iglesias-Pedraz JM, Chen LY, et al. Downregulation of the Werner syndrome protein induces a metabolic shift that compromises redox homeostasis and limits proliferation of cancer cells. Aging Cell. 2014,13(2):367-78.
Read this paper