G72 antibody
GTX117488
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetDAOA
Overview
- SupplierGeneTex
- Product NameG72 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID267012
- Target nameDAOA
- Target descriptionD-amino acid oxidase activator
- Target synonymsD-amino acid oxidase activator; LG72; schizophrenia- and bipolar disorder-associated protein G72; SG72
- HostRabbit
- IsotypeIgG
- Protein IDP59103
- Protein NameD-amino acid oxidase activator
- Scientific DescriptionThis gene encodes a protein that is an activator of the FAD-dependent enzyme D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder, possibly due to decreased levels of D-serine and decreased NMDA receptor functioning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Decreased level of serum autoantibody against LG72 is a biosignature of amyotrophic lateral sclerosis. Hwang CS et al., 2016, Biomark MedRead more