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ProductsBack/G72 antibody

Sample (30 ug of whole cell lysate) A: PC-3 12% SDS PAGE GTX117488 diluted at 1:1000

Sample (30 ug of whole cell lysate) A: PC-3 12% SDS PAGE GTX117488 diluted at 1:1000

Sample (30 ug of whole cell lysate) A: PC-3 12% SDS PAGE GTX117488 diluted at 1:1000

G72 antibody

GTX117488

ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Product group Antibodies

ReactivityHuman

TargetDAOA

Overview

Supplier
GeneTex
Product Name
G72 antibody
Delivery Days Customer
9
Application Supplier Note
WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID267012
Target name
DAOA
Target description
D-amino acid oxidase activator
Target synonyms
LG72, SG72, D-amino acid oxidase regulator, schizophrenia- and bipolar disorder-associated protein G72
Host
Rabbit
Isotype
IgG
Protein IDP59103
Protein Name
D-amino acid oxidase regulator
Scientific Description
This gene encodes a protein that is an activator of the FAD-dependent enzyme D-amino acid oxidase, which degrades the gliotransmitter D-serine, a potent activator of N-methyl-D-aspartate (NMDA) type glutamate receptors. Polymorphisms in this gene have been implicated in susceptibility to schizophrenia and bipolar affective disorder, possibly due to decreased levels of D-serine and decreased NMDA receptor functioning. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
Reactivity
Human
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

Hwang CS, Tsai CH, Liu GT, et al. Decreased level of serum autoantibody against LG72 is a biosignature of amyotrophic lateral sclerosis. Biomark Med. 2016,10(1):73-9. doi: 10.2217/bmm.15.80
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