GAB1 antibody
GTX111253
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetGAB1
Overview
- SupplierGeneTex
- Product NameGAB1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID2549
- Target nameGAB1
- Target descriptionGRB2 associated binding protein 1
- Target synonymsDFNB26, GRB2-associated-binding protein 1, GRB2-associated binder 1, deafness, autosomal recessive 26, growth factor receptor bound protein 2-associated protein 1
- HostRabbit
- IsotypeIgG
- Protein IDQ13480
- Protein NameGRB2-associated-binding protein 1
- Scientific DescriptionThe protein encoded by this gene is a member of the IRS1-like multisubstrate docking protein family. It is an important mediator of branching tubulogenesis and plays a central role in cellular growth response, transformation and apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Li Y, Wang H, Sun B, et al. Smurf1 and Smurf2 mediated polyubiquitination and degradation of RNF220 suppresses Shh-group medulloblastoma. Cell Death Dis. 2023,14(8):494. doi: 10.1038/s41419-023-06025-2Read this paper
- Hamam SM, Abdelzaher E, Fadel SH, et al. Prognostic value of microRNA-125a expression status in molecular groups of pediatric medulloblastoma. Childs Nerv Syst. 2023,39(7):1869-1880. doi: 10.1007/s00381-023-05899-zRead this paper





