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Immunohistochemistry of paraffin-embedded Human breast cancer using GAD1 Polyclonal Antibody at dilution of 1/20
Immunohistochemistry of paraffin-embedded Human breast cancer using GAD1 Polyclonal Antibody at dilution of 1/20
Immunohistochemistry of paraffin-embedded Human breast cancer using GAD1 Polyclonal Antibody at dilution of 1/20

GAD1 Polyclonal Antibody

E-AB-17390
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    GAD1 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
  • UNSPSC
    12352203