GADD45GIP1 Antibody
CSB-PA039959
Overview
- SupplierCusabio
- Product NameGADD45GIP1 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- HostRabbit
- IsotypeIgG
- Scientific DescriptionActs as a negative regulator of G1 to S cell cycle phase progression by inhibiting cyclin-dependent kinases. Inhibitory effects are additive with GADD45 proteins but occurs also in the absence of GADD45 proteins. Acts as a repressor of the orphan nuclear receptor NR4A1 by inhibiting AB domain-mediated transcriptional activity. May be involved in the hormone-mediated regulation of NR4A1 transcriptional activity. May play a role in mitochondrial protein synthesis. Goernemann J., Virology 303:69-78(2002). Chung H.K., J. Biol. Chem. 278:28079-28088(2003). The MGC Project Team, Genome Res. 14:2121-2127(2004).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203