GAK inhibitor 49

MedChem Express

GAK inhibitor 49 [319492-82-5]

10

319492-82-5

Research Use Only

98.79

C20H22N2O5

370.40

GAK inhibitor 49 is a potent, ATP-competitive and highly selective cyclin G associated kinase (GAK) inhibitor with a K i of 0.54 nM and a cell IC 50 of 56 nM. GAK inhibitor 49 also shows binding to RIPK2 [1] .

COC1=C(OC)C(OC)=CC(NC2=CC=NC3=CC(OC)=C(OC)C=C23)=C1

-20°C,2°C to 8°C

12352200