Various whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with Galectin 1 antibody (GTX116411) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.
Various whole cell extracts (30 μg) were separated by 15% SDS-PAGE, and the membrane was blotted with Galectin 1 antibody (GTX116411) diluted at 1:2000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody. Corresponding RNA expression data for the same cell lines are based on Human Protein Atlas program.
Galectin 1 antibody
GTX116411
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetLGALS1
Overview
- SupplierGeneTex
- Product NameGalectin 1 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:20000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.48 mg/ml
- ConjugateUnconjugated
- Gene ID3956
- Target nameLGALS1
- Target descriptiongalectin 1
- Target synonymsGAL1, GBP, galectin-1, 14 kDa laminin-binding protein, 14 kDa lectin, HBL, HLBP14, HPL, S-Lac lectin 1, beta-galactoside-binding lectin L-14-I, beta-galactoside-binding protein 14kDa, epididymis secretory sperm binding protein, gal-1, galaptin, lactose-binding lectin 1, lectin, galactoside-binding, soluble, 1, putative MAPK-activating protein PM12
- HostRabbit
- IsotypeIgG
- Protein IDP09382
- Protein NameGalectin-1
- Scientific DescriptionThe galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. This gene product may act as an autocrine negative growth factor that regulates cell proliferation. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Paz H, Joo EJ, Chou CH, et al. Treatment of B-cell precursor acute lymphoblastic leukemia with the Galectin-1 inhibitor PTX008. J Exp Clin Cancer Res. 2018,37(1):67. doi: 10.1186/s13046-018-0721-7Read this paper
- Mori Y, Akita K, Yashiro M, et al. Binding of Galectin-3, a β-Galactoside-binding Lectin, to MUC1 Protein Enhances Phosphorylation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) and Akt, Promoting Tumor Cell Malignancy. J Biol Chem. 2015,290(43):26125-40. doi: 10.1074/jbc.M115.651489Read this paper
- May EW, Lin ST, Lin CC, et al. Identification of up- and down-regulated proteins in doxorubicin-resistant uterine cancer cells: reticulocalbin-1 plays a key role in the development of doxorubicin-associated resistance. Pharmacol Res. 2014,90:1-17. doi: 10.1016/j.phrs.2014.08.007Read this paper
- Lin LH, Chang SJ, Hu RY, et al. Biomarker discovery for neuroendocrine cervical cancer. Electrophoresis. 2014,35(14):2039-45. doi: 10.1002/elps.201400014Read this paper
- Fan CY, Chou HC, Lo YW, et al. Proteomic and redox-proteomic study on the role of glutathione reductase in human lung cancer cells. Electrophoresis. 2013,34(24):3305-14. doi: 10.1002/elps.201300250Read this paper
Datasheet
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