Bio-Connect

GALNT6 antibody [N1C2]

GTX104602
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Rat
TargetGALNT6
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Overview

  • Supplier
    GeneTex
  • Product Name
    GALNT6 antibody [N1C2]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.17 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID11226
  • Target name
    GALNT6
  • Target description
    polypeptide N-acetylgalactosaminyltransferase 6
  • Target synonyms
    GalNAc transferase 6; GalNAcT6; GALNAC-T6; polypeptide GalNAc transferase 6; polypeptide N-acetylgalactosaminyltransferase 6; pp-GaNTase 6; protein-UDP acetylgalactosaminyltransferase 6; UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase 6; UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6 (GalNAc-T6)
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ8NCL4
  • Protein Name
    Polypeptide N-acetylgalactosaminyltransferase 6
  • Scientific Description
    This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. [provided by RefSeq]
  • Reactivity
    Human, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Role of N-acetylgalactosaminyltransferase 6 in early tumorigenesis and formation of metastasis. Liesche F et al., 2016 May, Mol Med Rep
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  • Glycosyltransferases as Markers for Early Tumorigenesis. Andergassen U et al., 2015, Biomed Res Int
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