GALR1 antibody [C2C3], C-term
GTX108207
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetGALR1
Overview
- SupplierGeneTex
- Product NameGALR1 antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID2587
- Target nameGALR1
- Target descriptiongalanin receptor 1
- Target synonymsGALNR, GALNR1, galanin receptor type 1, GAL1-R, GALR-1
- HostRabbit
- IsotypeIgG
- Protein IDP47211
- Protein NameGalanin receptor type 1
- Scientific DescriptionThe neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Kiezun J, Kiezun M, Krazinski BE, et al. Galanin Receptors (GALR1, GALR2, and GALR3) Immunoexpression in Enteric Plexuses of Colorectal Cancer Patients: Correlation with the Clinico-Pathological Parameters. Biomolecules. 2022,12(12). doi: 10.3390/biom12121769Read this paper
- Kiezun J, Godlewski J, Krazinski BE, et al. Galanin Receptors (GalR1, GalR2, and GalR3) Expression in Colorectal Cancer Tissue and Correlations to the Overall Survival and Poor Prognosis of CRC Patients. Int J Mol Sci. 2022,23(7). doi: 10.3390/ijms23073735Read this paper
- Ma W, Lyu H, Pandya M, et al. Successful Application of a Galanin-Coated Scaffold for Periodontal Regeneration. J Dent Res. 2021,100(10):1144-1152. doi: 10.1177/00220345211028852Read this paper
- Brunner SM, Reichmann F, Leitner J, et al. Galanin receptor 3 attenuates inflammation and influences the gut microbiota in an experimental murine colitis model. Sci Rep. 2021,11(1):564. doi: 10.1038/s41598-020-79456-yRead this paper
- Falkenstetter S, Leitner J, Brunner SM, et al. Galanin System in Human Glioma and Pituitary Adenoma. Front Endocrinol (Lausanne). 2020,11:155. doi: 10.3389/fendo.2020.00155Read this paper
- Koller A, Brunner SM, Bianchini R, et al. Galanin is a potent modulator of cytokine and chemokine expression in human macrophages. Sci Rep. 2019,9(1):7237. doi: 10.1038/s41598-019-43704-7Read this paper
- Schrödl F, Kaser-Eichberger A, Trost A, et al. Distribution of galanin receptors in the human eye. Exp Eye Res. 2015,138:42-51. doi: 10.1016/j.exer.2015.06.024Read this paper
Datasheet
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