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GALR1 antibody [C2C3], C-term

GTX108207
GeneTex
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetGALR1
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Overview

  • Supplier
    GeneTex
  • Product Name
    GALR1 antibody [C2C3], C-term
  • Delivery Days Customer
    9
  • Application Supplier Note
    IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.3 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID2587
  • Target name
    GALR1
  • Target description
    galanin receptor 1
  • Target synonyms
    GAL1-R; galanin receptor type 1; GALNR; GALNR1; GALR-1
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP47211
  • Protein Name
    Galanin receptor type 1
  • Scientific Description
    The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Galanin Receptors (GalR1, GalR2, and GalR3) Expression in Colorectal Cancer Tissue and Correlations to the Overall Survival and Poor Prognosis of CRC Patients. Kiezun J et al., 2022 Mar 29, Int J Mol Sci
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  • Galanin receptor 3 attenuates inflammation and influences the gut microbiota in an experimental murine colitis model. Brunner SM et al., 2021 Jan 12, Sci Rep
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  • Galanin System in Human Glioma and Pituitary Adenoma. Falkenstetter S et al., 2020, Front Endocrinol (Lausanne)
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  • Galanin is a potent modulator of cytokine and chemokine expression in human macrophages. Koller A et al., 2019 May 10, Sci Rep
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  • Distribution of galanin receptors in the human eye. Schroedl F et al., 2015 Sep, Exp Eye Res
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