GALR1 antibody [C2C3], C-term
GTX108207
ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetGALR1
Overview
- SupplierGeneTex
- Product NameGALR1 antibody [C2C3], C-term
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.3 mg/ml
- ConjugateUnconjugated
- Gene ID2587
- Target nameGALR1
- Target descriptiongalanin receptor 1
- Target synonymsGAL1-R; galanin receptor type 1; GALNR; GALNR1; GALR-1
- HostRabbit
- IsotypeIgG
- Protein IDP47211
- Protein NameGalanin receptor type 1
- Scientific DescriptionThe neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the brain and spinal cord, as well as in peripheral sites such as the small intestine and heart. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Galanin Receptors (GalR1, GalR2, and GalR3) Expression in Colorectal Cancer Tissue and Correlations to the Overall Survival and Poor Prognosis of CRC Patients. Kiezun J et al., 2022 Mar 29, Int J Mol SciRead more
- Galanin receptor 3 attenuates inflammation and influences the gut microbiota in an experimental murine colitis model. Brunner SM et al., 2021 Jan 12, Sci RepRead more
- Galanin System in Human Glioma and Pituitary Adenoma. Falkenstetter S et al., 2020, Front Endocrinol (Lausanne)Read more
- Galanin is a potent modulator of cytokine and chemokine expression in human macrophages. Koller A et al., 2019 May 10, Sci RepRead more
- Distribution of galanin receptors in the human eye. Schroedl F et al., 2015 Sep, Exp Eye ResRead more